Medical Cannabis for Chronic Pain. Clinical research.

When you need to take a medicine for pain, you sure that this medicine was tasted and has clinical researches dates.  Only scientific data, studies and statistics are reliable sources of information about the quality of a medicine.

In this article, I leave two links to clinical researches of CBD for chronic pain.

https://pubmed.ncbi.nlm.nih.gov/29637590/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878090/

Globally, chronic pain is a major therapeutic challenge and affects more than 15% of the population. As patients with painful terminal diseases may face unbearable pain, there is a need for more potent analgesics. Although opioid-based therapeutic agents received attention to manage severe pain, their adverse drug effects and mortality rate associated with opioids overdose are the major concerns.

Evidence from clinical trials showed therapeutic benefits of cannabis, especially delta-9-tetrahydrocannabinol and cannabinoids reduced neuropathic pain intensity in various conditions.

Also, there are reports on using combination cannabinoid therapies for chronic pain management. The association of cannabis dependence and addiction has been discussed much and the reports mentioned that it can be comparatively lower than other substances such as nicotine and alcohol. More countries have decided to legalise the medicinal use of cannabis and marijuana.

The National Academies of Sciences, Engineering, and Medicine has found substantial evidence that cannabis (plant) is effective for the treatment of chronic pain in adults, and moderate evidence that oromucosal cannabinoids (extracts, especially nabiximols) improve short-term sleep disturbances in chronic pain.

A number of research studies examined the efficacy of medical cannabis on treating chronic pain and other conditions. For example, the findings from a 2019 study published in the Journal of Psychoactive Drugs, which evaluated data from 1,000 individuals taking legalized cannabis in one state, found that among the 65% of individuals taking cannabis for pain, 80% found it was very or tremendously helpful. This led to 82% of these individuals being able to reduce, or halt, taking OTC pain medications and 88% being able to halt taking opioids.

In addition, results reported at the American Academy of Neurology 2019 Annual Meeting revealed that in a preliminary study, investigators at the Dent Neurologic Institute in Buffalo, New York, found that the cannabis provided elderly patients with relief from chronic pain, sleep disorders, and anxiety related to diseases such as amyotrophic lateral sclerosis, Parkinson disease, neuropathy, spinal cord damage, and multiple sclerosis.

Their findings show that medical cannabis is well tolerated in people aged 75 years and older and may improve symptoms such as chronic pain and anxiety.