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    6 days ago

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    Adjunctive cannabidiol offer long term efficacy for adult patients with Dravet’s and Lennox-Gastaut Syndromes’Gradual titration of Cannabidiol from 1mg/kg/day up to modest doses of up to 10mg/kg/day reduced the frequency of both focal and generalised seizures (GTCS) with ≥50% seizure reduction in over two thirds of the cohort. No patients became seizure free. Cannabidiol was well tolerated; over 95% of the cohort remained on the drug at last follow up. ... See MoreSee Less

    Adjunctive cannabidiol offer long term efficacy for adult patients with Dravet’s and Lennox-Gastaut Syndromes’

    jnnp.bmj.com

    To determine if Concomitant use of Cannabidiol and Clobazam can improve seizure control in patients with epileptic encephalopathies. Methods Epileptic encephalopathies are a disabling and life-limitin...
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    leafboutique2 leaf_boutique @leafboutique2 ·
    17 Nov

    Endometriosis: cannabidiol therapy for symptom relief: Trends in Pharmacological Sciences

    Reply on Twitter 1858110816706253118 Retweet on Twitter 1858110816706253118 Like on Twitter 1858110816706253118 Twitter 1858110816706253118
    leafboutique2 leaf_boutique @leafboutique2 ·
    15 Nov

    Adjunctive cannabidiol offer long term efficacy for adult patients with Dravet’s and Lennox-Gastaut Syndromes’

    Reply on Twitter 1857472444577071158 Retweet on Twitter 1857472444577071158 Like on Twitter 1857472444577071158 Twitter 1857472444577071158

    cannabis___chronicles

    cannabis___chronicles
    📰 Scientists discover cancer-fighting CBD compo 📰 Scientists discover cancer-fighting CBD compounds: a breakthrough in treatment. 🚨 Groundbreaking discovery in the fight against cancer! 🚨 Scientists have synthesized ring-annulated analogues of cannabidiol (CBD), a nonpsychoactive cannabinoid, and found them to be potent anticancer agents. 💡 These innovative compounds show promise in targeting and destroying cancer cells without harming healthy ones, making them a potential breakthrough in cancer treatment. 🌟 Highlights: - CBD-based analogues with enhanced potency against cancer cells - Targeted approach to destroy cancer cells while sparing healthy tissue - Potential for new anticancer therapies 🎉 In conclusion, this innovative research brings us one step closer to finding effective and targeted treatments for cancer patients worldwide 💖. Stay tuned for more updates on this promising field of science! 🔬 https://pubmed.ncbi.nlm.nih.gov/39563806/
    📰 New Hope for Endometriosis Sufferers! 💊🌿 New hope for women with Endometriosis! 🌸 Endometriosis is a chronic & incurable condition causing painful periods & fatigue, but recent advances suggest that CBD therapy may provide symptom relief! 💫 Highlights: - CBD has been shown to have activity in pathways contributing to endometriosis - Studies are exploring its use in clinical trials for pain management - Formulations of CBD-containing products vary, with some showing promising PK profiles 📝 Key points: - Endometriosis is a complex condition with limited therapeutic options - Cannabidiol (CBD) has potential as a treatment option for symptom relief - Research suggests that CBD may help manage pain and other symptoms associated with endometriosis 💖 Conclusion: Could cannabidiol therapy be the key to unlocking new treatments for this debilitating condition? Stay tuned for updates on this promising research! 🌟https://pubmed.ncbi.nlm.nih.gov/39547915/
    🚨 Groundbreaking Research Alert! 💥 High-dos 🚨 Groundbreaking Research Alert! 💥 High-dose chemotherapy is a common treatment for breast cancer, but it comes with a significant risk of cardiotoxicity due to the chemotherapy agent doxorubicin (DOX). Researchers have discovered that combining DOX with cannabidiol (CBD) can not only improve anticancer activity but also reduce cardiotoxic side effects! 💪 Here are the highlights: ✨ CBD and DOX combination shows improved antitumor effect and reduced cardiotoxicity. ✨ Tumor size and weight decreased significantly in mice treated with DOX, pretreatment CBD + DOX, and CBD + DOX. ✨ Simultaneous administration of CBD and DOX increased SOD2 and reduced iNOS, MMP2, and MMP9. ✨ Cardiac histopathological examination showed no signs of congestion or inflammation in mice treated with CBD + DOX. The study concluded that combining CBD with DOX can be a game-changer for breast cancer treatment. However, more research is needed to understand the potential risks associated with CBD alone. 💡 Stay tuned for more updates on this exciting breakthrough! 🎉 https://pubmed.ncbi.nlm.nih.gov/39503169/
    🌿💡 New Breakthrough in Alzheimer's Treatment 🌿💡 New Breakthrough in Alzheimer's Treatment! 🌿💡 **Highlights:** * CBD-rich oil shows promise as an effective treatment for Neuropsychiatric Symptoms (NPS) in Alzheimer's Disease (AD) * Reduces NPI-Q severity scores by 30% or more in just 3 months * Lowers caregiver distress levels, improving daily caregiving and emotional well-being In a groundbreaking study, researchers found that CBD-rich oil is a safe and effective therapy for treating NPS in AD patients. With no significant adverse effects reported, this natural treatment may provide relief for both patients and caregivers. The results suggest that alleviating NPS improves daily life and reduces caregiver burden, making it a promising alternative to current treatments. 🌟💪 This study opens doors to new possibilities in Alzheimer's treatment, providing hope for those affected by the disease. 🌟 https://pubmed.ncbi.nlm.nih.gov/39474242/
    📰 "Unlocking CBD's Potential: New Hope for Alco 📰 "Unlocking CBD's Potential: New Hope for Alcohol Addiction Treatment" 🚨 Breakthrough in Understanding Alcohol Use Disorder 🚨 Discover how Cannabidiol (CBD) may hold the key to protecting against alcohol-related damage! 💊 Researchers have found that CBD can modulate gene expression and protect human skin cells from harm caused by ethanol. Key Highlights: 💡 Low concentrations of CBD stimulate cellular metabolism and reduce cell death. 🧬 Transcriptome analysis reveals similar gene expression profiles in CBD-treated vs. control cells. 🌿 CBD impacts genes involved in extracellular matrix formation, which could aid fibrosis prevention. The study's findings suggest that CBD may be a valuable tool in preventing liver fibrosis and other complications associated with alcohol use disorder. Will CBD become the next big hope for AUD treatment? 💡 Only time will tell! https://pubmed.ncbi.nlm.nih.gov/39466591/
    🚨 Warning: The Risks of Cannabis During Pregnan 🚨 Warning: The Risks of Cannabis During Pregnancy! 🚨 Highlights: - Impairments in cognitive function and behavior - Brain structural and functional alterations - Increased risk of premature birth, low birth weight, and mental health issues - Potential harm to the fetus and placental insufficiency Pregnancy with cannabis use is a growing concern due to its potential adverse effects on both mothers and offspring. Research suggests that prenatal exposure to cannabis can lead to impairments in cognitive function and behavior, as well as structural and functional alterations in the brain. Women who use cannabis during pregnancy are at a higher risk of experiencing pregnancy complications such as premature birth, low birth weight, and mental health issues. The use of cannabis has been shown to negatively impact placental functioning and fetal growth, potentially contributing to developmental challenges in children exposed to it in utero. Longitudinal studies have revealed that these children face long-term developmental obstacles, including decreased cognitive abilities, reduced academic performance, and behavioral issues. To address this issue, a comprehensive strategy that integrates public health policy, education, and research initiatives is crucial. By implementing targeted strategies, we can mitigate potential health concerns for both current and future generations. Conclusion: 🤝 Let's prioritize the health and well-being of our children! 🌟 https://pubmed.ncbi.nlm.nih.gov/39459478/
    📰 "Breakthrough: CBD Kills Oral Cancer Cells!" 📰 "Breakthrough: CBD Kills Oral Cancer Cells!" 🌿💡 New Breakthrough: Cannabidiol (CBD) Found to Inhibit Oral Cancer Growth! 💡🌿 Scientists have discovered that cannabidiol, a main component of cannabis, can effectively kill cancer cells in human oral squamous cell carcinoma. Key Findings: - CBD reduces cancer cell viability by up to 99% - Cell cycle arrest and increased apoptosis (cell death) observed - Significant DNA damage detected, leading to cell death The potential therapeutic benefits of CBD as a new treatment option for oral squamous cell carcinoma are promising. Research suggests that higher doses of CBD (>25 μM) showed greater cytotoxic effects. This groundbreaking study opens doors to exploring the use of CBD in cancer therapy. Stay tuned for more on this exciting development! 💫 https://pubmed.ncbi.nlm.nih.gov/39426313/
    📰 Hope on the Horizon: Cannabinoids May Hold Ke 📰 Hope on the Horizon: Cannabinoids May Hold Key to Beating Colorectal Cancer 🌟 Researchers have made a groundbreaking discovery that offers new hope for colorectal cancer patients! 💪 Highlights: - New compounds with potential anticancer properties are being developed. - Cannabinoids, such as CBD and CBC, showed promising results in the study. Researchers studied the effects of cannabinoids on colon cancer cells. Their findings indicate that these compounds can induce apoptosis (cell death) by modulating mitochondrial activity and cellular membrane integrity. The tested cannabinoids also influenced cell cycle progression and showed antioxidant properties. This breakthrough suggests that cannabinoids could be an interesting target for further research into alternative or combined therapies for human colon cancer. 💡https://pubmed.ncbi.nlm.nih.gov/39404380/
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